Snoop Dogg, Will Ferrell, and John C. Reilly shared the stage at the Best Night of Your Life 2 benefit show 

They performed "Boats 'N Hoes," a song from the 2008 comedy "Step Brothers 

Afterward, they transitioned to Snoop Dogg's 1994 hit, "Gin and Juice 

John C. Reilly announced that Snoop Dogg had celebrated his 52nd birthday the day before 

The crowd at Los Angeles' Greek Theatre sang "Happy Birthday" to Snoop Dogg 

Will Ferrell brought out a giant birthday cake for the rapper 

Snoop Dogg used the birthday candles to light a joint, much to the delight of the crowd 

Snoop Dogg jokingly claimed to be the ultimate "plug" for various substances worldwide 

Snoop recently collaborated with Chris Stapleton and Cindy Blackman Santana to remake Phil Collins' "In the Air Tonight" for ESPN's Monday Night Football 

Will Ferrell showcased his DJ skills, playing popular songs at a fraternity event